Neurobion (medicine): what is it and what is it for?

What is the Neurobion and what is it for? Neurobion is the brand that gives its name to a vitamin medicine that contains three active substances: Thiamine mononitrate (Vitamin B1), Pyridoxine hydrochloride (Vitamin B6) and Cyanocobalamin (Vitamin B12).

The Neurobion is considered a medicine, since it has therapeutic effects. Its main indication is the use for pathologies related to the nervous and muscular system, as well as the maintenance of its correct functioning. In this article we will tell you everything about this drug.

Neurobion: characteristics and components

Neurobion is made up of three vitamins, all of them B vitamins, considered essential for metabolism and cellular functioning. Today we talk about the properties and characteristics of Neurobion, as well as contraindications, side effects and precautions that must be carried out to avoid problems derived from its use.

As we have already said, Neurobion is a multivitamin complex from the group of B vitamins. These vitamins are essential for various processes that occur in cells, such as metabolism of substances, participation in processes of oxidation-reduction of substances, synthesis of carbohydrates,

protein and fat, nerve impulse conduction, etc. For this reason, they are considered essential for the proper functioning of the body.

Neurobion vitamins

Below we explain in a summarized way the importance and role of each of the vitamins that it has the Neurobion in its composition, as well as possible deficiencies of these and its consequent impact on the organism.

1. Vitamin B1 or thiamine

Vitamin B1 is essential for the process of sugar metabolism, oxygen metabolism and nerve impulse conduction.. A deficiency of this vitamin can lead to diarrhea, weight loss and behavioral disturbances such as irritability, depression, forgetfulness and reduced ability to concentrate.

This vitamin is closely related to alcoholism, since this makes it difficult to absorb in the intestine. In addition, a diet excessively rich in sugars and refined cereals can also cause their deficit, since the Vitamin B1 is found in the husks of whole grains, which are lost in the processes of refinement.

2. Vitamin B6 or pyridoxine

Vitamin B6 plays a crucial role in the growth and reproduction of cells.

Its deficiency produces an enzymatic deficiency in the cells, resulting in possible DNA damage. Deficiencies in vitamin B6 can cause inflammation in the skin, as well as dry skin, eczema, anemia, diarrhea and even neuronal damage associated with dementias.

It is also related to prostate cancer, heart disease and brain problems in general. This vitamin is also widely used in menopausal women, as it alleviates some of the symptoms of this period.

3. Vitamin B12 or cobalamin

Vitamin B12 participates in the normal development of the nervous system. It is essential for the bone marrow and at the blood level it participates in the synthesis of erythrocytes, that is, red blood cells. It also participates in the proper functioning of the gastrointestinal tract.

Deficiencies in vitamin B12 can cause anemia, since this vitamin is involved in the synthesis of red blood cells, and without them, the body cannot properly bombard oxygen to the tissues of the Body.

It is important to know that these vitamins can be found in many foods (fish, meats, cereals, vegetables, etc) and that the deficiency states of any of these vitamins can be supplied by following a healthy diet and balanced.

Format and administration

The pharmaceutical form of Neurobion varies depending on the presentation. There are two formats: a box with 5 vials of 2 ml of solution for injection and 5 glass syringes with sterile needles. disposable or a box with 5 disposable prefilled syringes, each containing 2 ml of solution for injection and 5 sterile needles disposable.

Its administration can be oral or intramuscular and is usually every 24 or 48 hours. If administered orally (Release), the substances are Absorbed, Distributed, Metabolized and finally Eliminated (what is known as the LADME of pharmacokinetics). And in this way, a systemic effect of the product is obtained.

If, on the other hand, we administer intramuscularly, we avoid the absorption step, and a more effective effect is obtained. fast, apart from getting more vitamins to the body because we avoid losing part of the metabolism hepatic.

Indications and uses

As we have already mentioned, the vitamins present in the Neurobion are essential for the metabolism and functioning of cells. Therefore, used primarily to treat disorders involving deficiency of these three vitamins, and that they present with muscular and nervous type pains, such as low back pain, myalgia, sciatica, neuralgia, etc.

In these cases, the administration is carried out intramuscularly, since in this way the bioavailability of the drug (drugs in this case) is greater, and more active quantity reaches the body.

Contraindications

The use of Neurobion should be avoided if you have a known allergy or hypersensitivity to any of the vitamins. or to any of its excipients (that is, substances that are added to achieve the pharmaceutical form of the product).

Regarding excipients, one of the most common in its formats is benzyl alcohol, so it should be avoided during pregnancy and breastfeeding, and of course administered in newborns or children.

Adverse reactions

Like all medicine, Neurobion has possible adverse or unwanted effects. We must bear in mind that adverse reactions are unwanted reactions that occur with therapeutic concentrations of the drug and not necessarily under an overdose of said drug, so many times these reactions can be unavoidable.

The best known adverse reactions to Neurobion, although rare, are neurological adverse effects (neuropathy sensory), immune system disorders (excessive sweating and tachycardia) and gastrointestinal (gastrointestinal discomfort, nausea, vomiting diarrhea and abdominal pain).

Adverse effects on the skin and subcutaneous tissue (urticaria and eczema) have also been described, especially in those cases in which the administration is dermal, renal and urinary (chromaturia; discharge of urine of an abnormal color, usually reddish).

Neurobion can also cause photosensitivity reactions, that is, intense sensitivity to ultraviolet (UV) light or sunlight once the drug has been administered. This photosensitivity can cause skin rashes, fever, fatigue, joint pain. In these cases, it is best to avoid sun exposure during the first hours after Neurobion administration.

In conclusion

Finally, it is important to emphasize that the administration and use of Neurobion must always be subject to medical and / or pharmaceutical advice.

In the case that we suspect that we have a deficiency of these vitamins and / or we have symptoms of low back pain or pain muscles in general, we should not self-diagnose, nor consequently self-medicate, but go to professionals suitable.

Bibliographic references

• VvAa. (2015). Royal Spanish Pharmacopoeia. 5th edition. State Agency Official State Gazette.

• VvAa. (2015). National Form. 2nd edition. State Agency Official State Gazette.